I always carry one of these in my car >
http://www.stopngo.com/pocket-tire-plugger-for-all-tubeless-tires for repairing nail-type punctures by the road-side. Whilst they say it is just a quick-fix to get you to a tyre-repairer, I know loads of super-bike riders who just plug their tyres and carry on pushing their bikes to the limits. I've never heard of one of these repairs failing, and one of my mates had about four in his tyre before it wore out.
However, when it comes to run-flats, I found this post on another forum:
Why can't Run Flat Tyres be repaired?
The reason behind this, given by the tyre manufacturers is to do with the thickness of the RFT sidewalls. With a conventional tyre when a technician carries out a puncture repair, one of the first things they will do is to check the tyre for damage, especially damage to the sidewall. This damage is easy to spot as it shows up as creases in the sidewall when the tyre is deflated. With the RFT it is impossible to say for sure if the sidewall has been damaged as the sidewall is so much thicker. Therefore they have no option but to replace the tyre.
What about a slow puncture?
The damage to the sidewall could occur if you continued to drive on the flat tyre for more than the recommended distance (approx. 100 miles) or over the maximum speed of 50 mph. However what if you'd not driven the tyre at zero pressure, what if the car had been sat on your driveway for a few days and happened to deflate as a result of a slow puncture. Surely this tyre would be repairable? Despite there being no damage to the sidewall you won't find anyone that will repair this RFT tyre, the fact is they only have your word that the tyre had not been driven on at zero pressure and they could run into liability problems if the repaired tyre failed.
Verdict
So are Run Flat Tyres safe to repair? In theory yes they are, as long as they are not driven on.</font>